Biomaterials for
Tissue Repair and Regeneration
 
 

MEMBERS

Adam Celiz

Lecturer (Assistant Professor) 

Adam graduated with a first class bachelor's degree from the University of Brighton in Pharmaceutical and Chemical Sciences in 2006. He then gained a PhD in Chemistry from the University of Cambridge in the Melville Laboratory for Polymer Synthesis in 2010. There he worked with Prof. Oren Scherman developing supramolecular polymeric materials based on hydrogen bonding motifs. Adam then pursued postdoctoral research at the University of Nottingham in the Advanced Materials and Healthcare Technologies division, with Professors Morgan Alexander and Martyn Davies. Here he developed high-throughput screening methodologies to discover new biomaterials for stem cell interactions. This work led to Adam being awarded an Early Career Researcher Award from the American Vacuum Society's Biomaterials Interfaces Division. Following this, Adam travelled 'across the pond' and was awarded a Marie Curie International Outgoing fellowship to work with Professor David Mooney at Harvard University in the Wyss Institute for Biologically Inspired Engineering. Here Adam developed biomaterial-based strategies to repair and restore tissues. Following this fellowship, Adam was awarded the Larry Hench Young Investigators Prize by the UK Society for Biomaterials. In August 2017, Adam joined the Department of Bioengineering at Imperial College London as Lecturer (Assistant Professor) to develop new biomaterials for tissue repair and regeneration.

Adam's research has been published in the journals Science, Nature Materials and Advanced Materials and has been highlighted by news agenies such as the BBCNewsweek, Popular Science and the Telegraph

Ignacio Medina-Fernandez

PhD student

Ignacio obtained his BSc Degree in Biomedical Engineering in the Polytechnic University of Valencia in Spain. In October 2016, he joined Imperial College to study an MSc in Biomedical Engineering with a specialisation in Biomaterials and Tissue Engineering. In 2017, Ignacio joined the Celiz Lab to develop scaffolds for dentine-pulp regeneration.

 
 

NEWS

PUBLICATIONS

2019

Medina-Fernandez I.; Celiz A. D. “Acellular Biomaterial Strategies for Endodontic Regeneration” Biomaterials Science 2019, 44, 697. 2019 Emerging Investigators Issue

 

 

2018

 

Vining K. H.; Scherba J. C.; Bever A. M.; Alexander M. R.; Celiz A. D.*; Mooney D. J.* “Synthetic Light- Curable Polymeric Materials Provide a Supportive Niche for Dental Pulp Stem Cells” Advanced Materials 2018, 30, 1704486 – 1704489. 

2017

 

Li J.; Celiz A. D.*; Yang J.*; Yang Q.; Wamala I.; Whyte W.; Seo B. R.; Vasilyev N. V.; Vlassak J. J.; Suo Z.; Mooney D. J. “Tough Adhesives for Diverse Wet Surfaces” Science 2017, 357, 378 – 381.

Bauer A.; Gu L.; Kwee B.; Li A. W.; Dellacherie M.; Celiz A. D.; Mooney D. J. “Hydrogel Substrate Stress-Relaxation Regulates the Spreading and Proliferation of Mouse Myoblasts” Acta Biomaterialia 2017, 62, 82 – 90. 

2016

Amin Y. Y. I.; Runager K.; Simoes F.; Celiz A. D.; Taresco V.; Rossi R.; Enghild J. J.; Abildtrup L. A.; Kraft D. C. E.; Sutherland D. S.; Alexander M. R.; Foss M.; Ogaki R. “Combinatorial Biomolecular Nano-patterning for High-throughput Screening of Stem Cell Behavior” Advanced Materials 2016, 28, 1472 – 1476.

 

Patel A. K.; Tibbitt M. W.; Celiz A. D.; Langer R.; Davies M. C.; Denning C.; Alexander M. R.; Anderson D. G. “High Throughput Screening for Discovery of Materials that Control Stem Cell Fate” Current Opinion in Solid State and Materials Science 2016, 20, 202 – 211.

2015

 

Celiz A. D.*; Smith J. G. W.*; Patel A. K.; Hook A. L.; Rajamohan D.; George V. T.; Patel M. J.; Epa V. C.; Singh T.; Langer R.; Anderson D. G.; Allen N. D.; Hay D. C.; Winkler D. A.; Barrett D. A.; Davies M. C.; Young L. E.; Denning C.; Alexander M. R. “Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multi-Lineage Differentiation.” Advanced Materials 2015, 27, 4006 - 4012.

 

Patel A. K.; Celiz A. D.; Rajamohan D.;  Anderson D. G.; Langer R.; Davies M. C.; Alexander M. R.; Denning C. "A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays“ Biomaterials 2015, 61, 257 - 265.

 

Smith J. G. W.; Celiz A. D.; Patel A. K.; Short R. D.; Alexander M. R.; Denning C. “Scaling Human Pluripotent Stem Cell Expansion and Differentiation: Are Cell Factories Becoming a Reality?” Regenerative Medicine 2015, 10, 925 – 930.

2014

 

Celiz A. D.; Smith J. G. W.; Langer R.; Anderson D. G.; Barrett D. A.; Winkler D. A.; Davies M. C.; Young L. E.; Denning C.; Alexander M. R. “Materials for Stem Cell Factories of the Future.” Nature Materials 2014, 13, 570 - 579.

 

Celiz A. D.; Smith J. G. W.; Patel A. K; Langer R.; Anderson D. G.; Barrett D. A.; Young L. E.; Davies M. C.; Denning C.; Alexander M. R. “Chemically Diverse Polymer Microarrays and High Throughput Surface Characterization: A Method for Discovery of Materials for Stem Cell Culture” Biomaterials Science 2014, 2, 1604 - 1611.

 

Celiz A. D.; Harrington H. C.; Hook A. L. “High Throughput Assessment and Chemometric Analysis of the Interaction of Epithelial and Fibroblast Cells with a Polymer Library” Applied Surface Science 2014, 313, 926 – 935.

2013

Rao W.; Celiz A. D.; Scurr D. J.; Alexander M. R.; Barrett D. A. “Ambient DESI and LESA-MS Analysis of Proteins Adsorbed to a Biomaterial Surface Using In-Situ Surface Tryptic Digestion.” Journal of the American Society for Mass Spectrometry 2013, 24, 1927 – 1936.

 

Celiz A. D.; Hook A. L.; Scurr D. J.; Anderson D. A.; Langer, R.; Davies M. C.; Alexander, M. R. “ToF-SIMS imaging of a Polymer Microarray prepared using Ink-Jet Printing of Acrylate Monomers.” Surface and Interface Analysis 2013, 45, 202 - 205.

2010

 

Celiz A. D.; Scherman O. A. “A Facile Route to Ureidopyrimidinone-Functionalized Polymers via RAFT Polymerization.” Journal of Polymer Science Part A: Polymer Chemistry 2010, 48, 5833 – 5841.

2009

 

Celiz A. D.; Lee T. C.; Scherman O. A. “Polymer-Mediated Dispersion of Gold Nanoparticles Using Supramolecular Moieties on the Periphery.” Advanced Materials 2009, 21, 3937 - 3940.

2008

 

Celiz A. D.; Scherman O. A. “Controlled Ring-Opening Polymerization Initiated via Self Complementary Hydrogen-Bonding Units.” Macromolecules 2008, 41, 4115 - 4119. 

 
 

CONTACT

Royal School of Mines

Room 4.37

South Kensington Campus

Imperial College London

London, SW7 2AZ

UK