Tissue Repair and Regeneration
Lecturer (Assistant Professor)
Adam graduated with a first class bachelor's degree from the University of Brighton in Pharmaceutical and Chemical Sciences in 2006. He then gained a PhD in Chemistry from the University of Cambridge in the Melville Laboratory for Polymer Synthesis in 2010. There he worked with Prof. Oren Scherman developing supramolecular polymeric materials based on hydrogen bonding motifs. Adam then pursued postdoctoral research at the University of Nottingham in the Advanced Materials and Healthcare Technologies division, with Professors Morgan Alexander and Martyn Davies. Here he developed high-throughput screening methodologies to discover new biomaterials for stem cell interactions. This work led to Adam being awarded an Early Career Researcher Award from the American Vacuum Society's Biomaterials Interfaces Division. Following this, Adam travelled 'across the pond' and was awarded a Marie Curie International Outgoing fellowship to work with Professor David Mooney at Harvard University in the Wyss Institute for Biologically Inspired Engineering. Here Adam developed biomaterial-based strategies to repair and restore tissues. Following this fellowship, Adam was awarded the Larry Hench Young Investigators Prize by the UK Society for Biomaterials. In August 2017, Adam joined the Department of Bioengineering at Imperial College London as Lecturer (Assistant Professor) to develop new biomaterials for tissue repair and regeneration.
Adam's research has been published in the journals Science, Nature Materials and Advanced Materials and has been highlighted by news agenies such as the BBC, Newsweek, Popular Science and the Telegraph
Dr. Nicola Contessi-Negrini
Nicola graduated in 2014 in Biomedical Engineering at Politecnico di Milano (Milan, IT) and received his European PhD in Bioengineering in 2018 at Politecnico di Milano, working on the development of hydrogel-based scaffolds for soft tissue regeneration via advanced fabrication technologies. He has been a visiting researcher at the University of Brighton (Brighton, UK), Warsaw University of Technology (Warsaw, PL), and Massachusetts Institute of Technology (Cambridge, MA, USA). Nicola joined the Celiz Lab as PostDoctoral Research Associate in 2019 to develop biomaterials to support dental tissue engineering.
Ignacio obtained his BSc Degree in Biomedical Engineering in the Polytechnic University of Valencia in Spain. In October 2016, he joined Imperial College to study an MSc in Biomedical Engineering with a specialisation in Biomaterials and Tissue Engineering. In 2017, Ignacio joined the Celiz Lab to develop scaffolds for dentine-pulp regeneration.
Medina-Fernandez I.; Celiz A. D. “Acellular Biomaterial Strategies for Endodontic Regeneration” Biomaterials Science 2019, 44, 697. 2019 Emerging Investigators Issue
Vining K. H.; Scherba J. C.; Bever A. M.; Alexander M. R.; Celiz A. D.*; Mooney D. J.* “Synthetic Light- Curable Polymeric Materials Provide a Supportive Niche for Dental Pulp Stem Cells” Advanced Materials 2018, 30, 1704486 – 1704489.
Li J.; Celiz A. D.*; Yang J.*; Yang Q.; Wamala I.; Whyte W.; Seo B. R.; Vasilyev N. V.; Vlassak J. J.; Suo Z.; Mooney D. J. “Tough Adhesives for Diverse Wet Surfaces” Science 2017, 357, 378 – 381.
Bauer A.; Gu L.; Kwee B.; Li A. W.; Dellacherie M.; Celiz A. D.; Mooney D. J. “Hydrogel Substrate Stress-Relaxation Regulates the Spreading and Proliferation of Mouse Myoblasts” Acta Biomaterialia 2017, 62, 82 – 90.
Amin Y. Y. I.; Runager K.; Simoes F.; Celiz A. D.; Taresco V.; Rossi R.; Enghild J. J.; Abildtrup L. A.; Kraft D. C. E.; Sutherland D. S.; Alexander M. R.; Foss M.; Ogaki R. “Combinatorial Biomolecular Nano-patterning for High-throughput Screening of Stem Cell Behavior” Advanced Materials 2016, 28, 1472 – 1476.
Patel A. K.; Tibbitt M. W.; Celiz A. D.; Langer R.; Davies M. C.; Denning C.; Alexander M. R.; Anderson D. G. “High Throughput Screening for Discovery of Materials that Control Stem Cell Fate” Current Opinion in Solid State and Materials Science 2016, 20, 202 – 211.
Celiz A. D.*; Smith J. G. W.*; Patel A. K.; Hook A. L.; Rajamohan D.; George V. T.; Patel M. J.; Epa V. C.; Singh T.; Langer R.; Anderson D. G.; Allen N. D.; Hay D. C.; Winkler D. A.; Barrett D. A.; Davies M. C.; Young L. E.; Denning C.; Alexander M. R. “Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multi-Lineage Differentiation.” Advanced Materials 2015, 27, 4006 - 4012.
Patel A. K.; Celiz A. D.; Rajamohan D.; Anderson D. G.; Langer R.; Davies M. C.; Alexander M. R.; Denning C. "A defined synthetic substrate for serum-free culture of human stem cell derived cardiomyocytes with improved functional maturity identified using combinatorial materials microarrays“ Biomaterials 2015, 61, 257 - 265.
Smith J. G. W.; Celiz A. D.; Patel A. K.; Short R. D.; Alexander M. R.; Denning C. “Scaling Human Pluripotent Stem Cell Expansion and Differentiation: Are Cell Factories Becoming a Reality?” Regenerative Medicine 2015, 10, 925 – 930.
Celiz A. D.; Smith J. G. W.; Langer R.; Anderson D. G.; Barrett D. A.; Winkler D. A.; Davies M. C.; Young L. E.; Denning C.; Alexander M. R. “Materials for Stem Cell Factories of the Future.” Nature Materials 2014, 13, 570 - 579.
Celiz A. D.; Smith J. G. W.; Patel A. K; Langer R.; Anderson D. G.; Barrett D. A.; Young L. E.; Davies M. C.; Denning C.; Alexander M. R. “Chemically Diverse Polymer Microarrays and High Throughput Surface Characterization: A Method for Discovery of Materials for Stem Cell Culture” Biomaterials Science 2014, 2, 1604 - 1611.
Celiz A. D.; Harrington H. C.; Hook A. L. “High Throughput Assessment and Chemometric Analysis of the Interaction of Epithelial and Fibroblast Cells with a Polymer Library” Applied Surface Science 2014, 313, 926 – 935.
Rao W.; Celiz A. D.; Scurr D. J.; Alexander M. R.; Barrett D. A. “Ambient DESI and LESA-MS Analysis of Proteins Adsorbed to a Biomaterial Surface Using In-Situ Surface Tryptic Digestion.” Journal of the American Society for Mass Spectrometry 2013, 24, 1927 – 1936.
Celiz A. D.; Hook A. L.; Scurr D. J.; Anderson D. A.; Langer, R.; Davies M. C.; Alexander, M. R. “ToF-SIMS imaging of a Polymer Microarray prepared using Ink-Jet Printing of Acrylate Monomers.” Surface and Interface Analysis 2013, 45, 202 - 205.
Celiz A. D.; Scherman O. A. “A Facile Route to Ureidopyrimidinone-Functionalized Polymers via RAFT Polymerization.” Journal of Polymer Science Part A: Polymer Chemistry 2010, 48, 5833 – 5841.
Celiz A. D.; Lee T. C.; Scherman O. A. “Polymer-Mediated Dispersion of Gold Nanoparticles Using Supramolecular Moieties on the Periphery.” Advanced Materials 2009, 21, 3937 - 3940.
Celiz A. D.; Scherman O. A. “Controlled Ring-Opening Polymerization Initiated via Self Complementary Hydrogen-Bonding Units.” Macromolecules 2008, 41, 4115 - 4119.
Royal School of Mines
South Kensington Campus
Imperial College London
London, SW7 2AZ